I do a 2 quart enema twice a month cause I have constipation and I only use water
if you use enough to fully clean your bowels out it will hurt but if you rub your gut in a counter-clockwise direction as you drain the enema into your bowels it doesn't hurt as much, the uncomfortable feeling is from the enema filling you up, if you receive a stabbing pain during this time stop cause it means that the enema is trying to enter your stomach