I've been a pantspooper for many years, and several years ago began taking Immodium AD as a means to firm up my stools and make it a bit more pleasureable to poop in my pants. I was taking about 6 immodium tablets a day, usually about 3 hours apart. I wasn't taking the pills with meals, but just swallowing them down with sip of water or soda. I noticed that the pills tended to upset my stomach a bit, but really didn't pay too much attention to it. I mean, really... Rite Aid isn't going to sell me something harmfull, are they?
Well it turned out that they did. I developed a case of EROSIVE GASTRITIS, which is a condition where there are eroded, open pit-like lesions in the wall of the stomach that bleed. I noticed some darkening of my stool, but I didn't think it was too bad. Several weeks later when I had some blood work done, it was found that I was severly anemic, due to the bleeding in my stomach. My gastro-enterologist told me that erosive gastritis can result in TORRENTIAL BLEEDING, which can KILL YOU in about two minutes. If torrential bleeding starts, and you're already in an emergency room, they MIGHT be able to save you, but no guarantee.
My phamacist told me the Immodium AD is "very hard in the stomach and intestine", and should ALWAYS be taken with meals. In adition, you shouldn't take these pills for more than one day every couple of weeks, to give your system the chance to recover. I use them about twice a month, making sure I take the pills on a full stomach, and never more than 5 or 6 pills a day. They work great, and I end up with a nice big firm load of shit to dump in my pants. I usually get a 2nd nice firm load the next day without have to take more Immodium.
So: ALWAYS take these pills with a full stomach, and NEVER take more than 6 pills a day.