I've been on diuretics before but had to stop due to the side effects. It's worth noting that they only make you pee a LOT when you first start taking it. But once stabalized, it's just water in water out.
However, they will continue to flush vitamins from your system. I ended up needing potassium and iron infusions because of the diuretics. So if you're one it, make sure your doctor is also getting a full blood panel done for you at least once a year. And consider taking a daily multivitamin.